Around the globe attractive, athletic young girls are disappearing. They are imprisoned for 6 years in an island fortress and subjected to a brutal training regime. After six years of training, the girls are finally forced to fight each other to the death. Three survive the ordeal the temperamental loner Jing (Jewel Lee) and close friends Charlene (Maggie Q) and Katt (Anya) and become professional assassins. When their activities attract the attentions of the CIA, Asian American agent Jack Chen (Daniel Wu) is assigned to investigate.